Do you regularly use cannabis? We are interested in understanding the cause of cannabis withdrawal syndrome and how it affects the brain. We are looking for participants who are 17-65 years of age who regularly use cannabis are willing to abstain from using cannabis for approximately 1 week. The goal of this study is to take pictures of a brain enzyme called fatty acid amide hydrolase (FAAH), which may be implicated in cannabis withdrawal syndrome. Knowing more about this enzyme can help us contribute to the development of new treatments and learn more about how it affects those with cannabis withdrawal syndrome. The study sessions include:
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1. An in-person interview (~4 hours). Here we will receive your consent to continue with the study.
2. 2 to 3 magnetic resonance imaging (MRI) sessions (~2 hours each)
3. 2 to 3 positron emission tomography (PET) sessions (~5-6 hours each)
4. Clinical visits/abstinence monitoring between PET scan 1 and PET scan 2 (~1 hour)
You will receive compensation for your time.
Also, expenses including travel and meals that fall within the study sessions can be reimbursed. For more information about the study (REB Ref# 029/2017), please contact: Nadia Boachie